Skip to main content. Home Information and support Facing breast cancer Going through breast cancer treatment Hormone therapy. Tamoxifen Fulvestrant Faslodex. What are aromatase inhibitors? The three aromatase inhibitor drugs are: letrozole anastrozole exemestane Men with breast cancer may be given an aromatase inhibitor, although another drug called tamoxifen is more commonly used. Is there a difference between letrozole, anastrozole and exemestane?
Which aromatase inhibitor causes the fewest side effects? People often ask if one drug causes fewer side effects than the others. Median duration of follow-up was 65 months. The 5-year estimated disease-free survival rate was Median disease-free survival was not reached in either group. Exploratory analysis showed similar 5-year disease-free survival rates with letrozole vs anastrozole in all evaluated subgroups, including among those with HER2-positive The 5-year estimated overall survival rate was Median overall survival was not reached in either group; at final analysis, death had occurred in Median time to distant metastases was not reached in either group; distant metastases occurred in Secondary malignancies occurred in 4.
Of patients, 49 In conclusion, both AIs are equally well tolerated. There were no significant differences in QOL scores between the two drugs. Abstract Previous studies have demonstrated that both anastrozole and letrozole are well tolerated.
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