And weight regain is common after 6 months, the point when such programs can yield weight loss of 5 percent to 10 percent. Weight-loss medications are one way to help more people to have larger, and potentially longer lasting, responses to lifestyle interventions, as placebo-controlled trials have shown. But these medications tend not to be used broadly, mainly because of lack of insurance coverage, leading to high out-of-pocket costs for patients, but also because of concerns about side effects.
Phentermine is the most commonly used anti-obesity medication in the United States. Many doctors prescribe phentermine, on its own, to patients for more than 12 weeks. And anecdotal reports from many of my colleagues suggested that it was helpful for many patients long-term. Phentermine is available as an inexpensive generic medication, but concerns have been raised about addiction and, because of how it acts, cardiovascular side effects.
We clearly needed more research to understand the benefits and risk of longer-term phentermine use. We studied nearly 14, phentermine users, 8 in 10 of whom were women. Obesity starts at a BMI of Three in 10 of them were prescribed phentermine for more than 3 months.
This also goes with elevated blood pressure, phentermine is absorbed from the GI tract and thus reaches the peak concentration level in Some of the effects show the drug has taken its place in the brain and working.
These are:. Phentermine extended-release capsules are also available which is taken once in the morning. The tablets, however, were taken 30 minutes before each meal three times per day. Due to its selective ability to interfere with neurotransmitters, Phentermine is classified as a controlled substance and only available over the prescription.
In many studies, Phentermine in a combination with restrictive diet and exercise promotes weight loss, which is more than the placebo group or only restrictive-diet following group.
Because phentermine for weight loss is recommended for the short-term only, any long-term effects on sustained weight loss might not be promising. According to the National Institute of Diabetes and Digestive and Kidney Disorders, most people after stopping weight loss medications regains the weight under months. Phentermine produces dangerous side effects in people with cardiovascular conditions, addiction history, or psychopathic episodes.
If you are experiencing any unwanted outcome from Phentermine, you should alert your doctor and stop taking it right away. Phentermine is involved in the modification of certain neurotransmitters such as Dopamine, Norepinephrine, and Serotonin. The effects are very similar to Amphetamine therefore it is strictly being given for a short time. None of the users with stimulant use disorder should be given Phentermine as it might elevate the psychotic episodes and aid addiction.
If you are scared of Phentermine staying in your system for such a long time, try having a different approach. Weight loss is the commonly searched problem so are the best weight loss pills. As an alternative to phentermine for weight loss, many types of natural dietary supplements are being made that deliver the same exact results WITHOUT the side effects. Metabolism of Adipex may take longer in an older person. If you are taking more than the recommended dose and using it off-label, Adipex may stay in your system longer.
A person of average build and metabolism can expect phentermine to be present in urine for three to five days. It may be longer for an older person. It is recommended to taper Adipex use rather than immediately stopping. Adipex will generally be out of your system about two days after the last time you take it.
Phentermine is stored in body fat and burning fat may support elimination. That said, there is no healthy way to speed up this process. If you are expecting to be tested for Adipex, disclose that you are taking it or stop using it prior to being tested. People prescribed Adipex for weight loss often expect to take it for several weeks.
Plan ahead. Keep in mind that if you are using the drug as prescribed by your doctor, it is not a problem for Adipex to show up on a drug test. Phentermine has stimulant properties and can impact neurotransmitters including dopamine, norepinephrine, and serotonin. This is very similar to amphetamines. For this reason, prescriptions are tightly regulated and often only allowed for short periods of time.
It is not recommended for people with a history of stimulant use disorder. Some of the serious side effects of Adipex include increased blood pressure, heart palpitations, restlessness, dizziness, tremor, insomnia, shortness of breath, chest pain, and swelling of the legs and ankles.
Adipex overdose symptoms, on the other hand, may include:. If you think someone has overdosed on any phentermine medication, call the poison control center at If the victim has collapsed or is not breathing, call immediately.
It is important that you discuss all of your medications and supplements with your doctor to avoid drug interactions. Drugs of special concern include those used to treat depression and similar conditions, including:. Your doctor should also be made aware of any previous heart conditions, including high blood pressure and arteriosclerosis, or if you have hyperthyroidism. It's also best to avoid using alcohol while taking Adipex as the combination can intensify the effects.
Withdrawal symptoms from Adipex use tend to peak within the first couple of days and diminish over the next week. Common withdrawal symptoms from Adipex include:. If you are taking Adipex regularly at a high dose and stop taking it too soon, you can be at risk for more serious problems, including:.
Adipex and other phentermine-containing medications may be available by prescription and can help with your weight loss goals. However, it is important to realize that there are potential risks involved, including developing a dependence and even a stimulant use disorder. It could become difficult for you to concentrate without taking Adipex.
You could enter into unhealthy cycles of taking more and less of the drug that put dangerous strain on your cardiovascular system. Cravings for Adipex that end up interfering with your everyday life are cause for speaking with a mental health professional.
Counseling or group therapy can help you understand the reasons for your Adipex use and develop alternatives and strategies to slowly stop using.
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